12/05/2020
Marie Skłodowska-Curie Actions
Science 4 Refugees

3 full-time Early Stage Researcher (ESR) positions at HeatNMof Project

This job offer has expired


  • ORGANISATION/COMPANY
    Fundacion IMDEA Energia
  • RESEARCH FIELD
    Biological sciencesBiological engineering
    Chemistry
    EngineeringBiomaterial engineering
    PhysicsChemical physics
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/06/2020 17:00 - Europe/Brussels
  • LOCATION
    Multiple locations, see work locations below.
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    ca. 40
  • OFFER STARTING DATE
    01/11/2020
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • MARIE CURIE GRANT AGREEMENT NUMBER
    860942
  • IS THE JOB RELATED TO STAFF POSITION WITHIN A RESEARCH INFRASTRUCTURE?
    Yes

We are happy to announce the availability of 3 Early Stage Researcher (ESR) positions of EU Marie Sklodowska-Curie Actions (MSCA) funded by the HeatNMof H2020 project, an EU Innovative Training Network of MSCA.

About HeatNMof

HeatNMof aims to develop smart multifunctional drug nanocarriers based on versatile porous biocompatible nanometric Metal Organic Frameworks, associated with exceptional drug payloads and controlled releases, and photo- and/or magnetic inorganic nanoparticles, providing both a specific control of reactions inside living entities and additional properties such as imaging and/ or hyperthermia therapy. The successful development of this project, involving academic and industrial partners, will contribute not only to improve the highly societal relevant cancer therapy but also to train the next generation of materials scientists in a highly interdisciplinary and intersectorial research environment.

The HeatNMof consortium includes the following 10 European institutions as Beneficiaries (3 industrial companies, 3 research centers and 4 academics): IMDEA Energy Institute, Spain; Universidad Santiago de Compostela, Spain; Centre National de la Recherche Scientifique, France; University of Antwerp, Belgium; Immaterial Labs LTD, United Kingdom; Institut National des Sciences Appliquées de Toulouse, France; University of Hamburg, Germany; Fondazione Istituto Italiano di Tecnologia, Italy; Nanoscale Biomagnetics SL, Spain; ISERN Patentes y Marcas M SL, Spain. The HeatNMof program is coordinated by Patricia Horcajada (IMDEA Energy Institute, Spain).

Job description

ESR8

  • Project Title: Design of a flexible manufacturing process for MOF scale up synthesis

  • PhD Objectives: To design a flexible manufacturing process for several variants of nanoMOF materials with a wide range of characteristics for drug delivery. The student selected for this project will be trained on green synthesis chemical techniques, powder X-ray diffraction, gas adsorption, electron and super-resolution microscopy and will join a growing interdisciplinary team.

  • Hosting institution: Immaterial Ltd. The successful applicant is expected to register for PhD at University of Cambridge (Cambridge, UK) in 2020.

  • Expected starting date: September-November 2020

  • Contact details for application: To apply send an email to Dr. Andrew Marsden in copy to Dr David Fairen-Jimenez and Prof. Clemens Kaminski with the subject "ESR8"; e-mail: a.marsden@immaterial.co, in cc to df334@cam.ac.uk and cfk23@cam.ac.uk.

ESR10

  • Project Title: Design, characterization and invitro application of coupling AMF applicator to fluorescence microscope.

  • PhD Objectives: The aim of this PhD project is to develop a coupling AMF applicator for confocal microscope and study the thermal and electromagnetic phenomena in biological material. His/her tasks will also include the study of nanomagnetism, numerical modeling of electromagnetic and heat phenomena in condensed matter, luminescence and fluorescent materials and high-power radiofrequency applicators.

  • Hosting institution: NanoScale Biomagnetics SL. The successful applicant is expected to register for PhD at University of Zaragoza (UNIZAR), Spain in 2020, and deploy activities both at the Institute of Nanoscience of Aragón (INA), UNIZAR and also at the facilities of the hiring company, nanoScale Biomagnetics SL.

  • Expected starting date: November 2020

  • Contact details for application: To apply send an email to Beatriz Sanz with the subject "ESR10", e-mail: bea@nbnanoscale.com

ESR12

  • Project Title: Plasmonic nanocomposites for photo-triggered drug release

  • PhD Objectives: The aim of this project is the loading of cells with MOFs, which are modified by plasmonic nanoparticles. The uptake pathway of the MOFs will be monitored by different experimental techniques, such as ICP-MS, fluorescence microscopy and flow cytometry. Location in endosomes/lysosomes will be verified by immunostaining techniques. Upon application of light excitation, local heat will be generated by the plasmonic nanoparticles, leading to transient rupture of the endosomal/lysosomal membranes and subsequent (partial) release of the MOFs, and molecules which has been encapsulated in the MOFs to the cytosol. This release will be determined quantitatively. Cells viability during this process will be monitored. This photo-triggered release will be also compared to other release techniques.

  • Hosting institution: INF, Universität Hamburg (https://www.physik.uni-hamburg.de/en/inf.html). The PhD title can be obtained either at the physics or chemistry faculty.

  • Expected starting date: September-November 2020

  • Contact details for application: To apply send an email to Wolfgang Parak with the subject "ESR12", e-mail: Wolfgang.Parak@uni-hamburg.de.

Benefits

The successful candidates will receive an attractive salary in accordance with the MSCA regulations for Early Stage Researchers. The exact (net) salary will be confirmed upon appointment and is dependent on local tax regulations and on the country correction factor (to allow for the difference in cost of living in different EU Member States). The salary includes a living allowance, a mobility allowance and a family allowance (if married). The guaranteed PhD funding is for 36 months (i.e. EC funding, additional funding is possible, depending on the local Supervisor, and in accordance with the regular PhD time in the country of origin). In addition to their individual scientific projects, all fellows will benefit from further continuing education, which includes internships and secondments (ca. 10 months), a variety of training modules as well as transferable skills courses and active participation in workshops and conferences.

Eligibility criteria

Applicants must satisfy the eligibility requirements for an ESR under the Horizon 2020 ITN Programme at the date of recruitment; in particular, they should be eligible to be appointed as an ESR by satisfying the following criteria:

• to have less than 4 years research careers after Undergraduate/Masters graduation (this is cumulative research experience and does not include management/industrial or other work experience);

• to not hold a PhD degree (PhD candidates under 4 years of registration and before completion may apply);

• to not have resided or carried out their main activity (work, studies, etc) in the host country for more than 12 months (cumulative) in the three years immediately before their recruitment (meant as the first day of the employment of the researcher for the purposes of the action (i.e. the starting date indicated in the contract). Compulsory national service and short stays such as holidays are not taken into account.

How to apply

Selection process

How to apply

Interested applicants should send an e-mail before the 15th of June 2020 at 5:00 PM CET to the contact person for each position (see details in Job description). Applications should enclose the following documents:

(a) your Europass CV

(b) a personal motivation letter describing in detail the reasons behind your professional choice to join our doctoral training program (400 words)

(c) copies of academic certificates and transcripts, including (if finished) a copy of your MSc thesis

(d) a brief research proposal addressing the topic of the research project (500-1000 words)

(e) Proof of language proficiency: Language certificate, university studies in the relevant language, research stay, etc.

(f) Optional: Supporting letters

 

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Biological sciences: Master Degree or equivalent
    Chemistry: Master Degree or equivalent
    Engineering: Master Degree or equivalent
    Pharmacological sciences: Master Degree or equivalent
    Physics: Master Degree or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

• Good self-management skills to work independently on a high scientific level. High motivation.

• Team player skills and enthusiasm to work in a multi-disciplinary, intersectoral and collaborative environment.

• To have analytical mind and excellent ability to express technical concepts and conclusions.

• Accredited good communication skills in English (both written and spoken) are mandatory.

 

Specific Requirements

ESR8

• Applicants should have a Master of Engineering or Master in Science (or equivalent; allowing the candidate to embark in a PhD in the hosting country).

• A background in chemistry, materials science or closely related disciplines is required; previous experience with MOF materials is preferable.

ESR10

• Bachelor’s degree in Physics or Engineering

• MSc degree (or equivalent; allowing the candidate to embark in a PhD in the hosting country) in Physics, Materials Science, or Engineering-related.

• Experience on numerical simulation of magnetic problems.

ESR12

• MSc degree (or equivalent; allowing the candidate to embark in a PhD in the hosting country) in Biology, Biotechnology, Chemistry, Nanoscience, Materials Science, Physics, or Medicine with previous experience in the interaction of nanoparticles with cells.

• Experience in standard particle characterization methods and cell culture techniques would be helpful, as well as knowledge with microscopy or flow cytometry.

 

Work location(s)
1 position(s) available at
Immaterial Ltd
United Kingdom
Cambridge
CB4 0FW
25 Cambridge Science Park, Milton Road
1 position(s) available at
NanoScale Biomagnetics SL.
Spain
Zaragoza
50197
Calle Alaún, 14, Nave 7
1 position(s) available at
Universität Hamburg
Germany
Hamburg
20146
Martin-Luther-King-Platz 6

EURAXESS offer ID: 522351

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