28/04/2021
Marie Skłodowska-Curie Actions

Postdoctoral researcher for MSCA-IF-2021 call: dietary polyphenols and human health

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  • OFFER DEADLINE
    22/05/2021 12:30 - Europe/Brussels
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • LOCATION
    Spain, Madrid
  • ORGANISATION/COMPANY
    ictan-csic
  • DEPARTMENT
    Metabolism and Nutrition
  • LABORATORY
    POLIFIBAN (non-extractable polyphenols, antioxdiants and dietary fibre in health)

We are looking for a candidate from outside Spain who plan to submit applications for independent research fellowships through the mobility program Marie Skłodowska Curie Individual Fellowship (MSCA-IF). The candidate would join the POLIBIBAN (non-extractable polyphenols, antioxidants and dietary fibre in health), at the Department of Metabolism and Nutrition, of the Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), in Madrid, Spain.

ICTAN-CSIC

The Spanish National Research Council (CSIC) is the largest public institution dedicated to research in Spain and the third largest in Europe. Its research is driven by more than 100 hundreds centres and institutes and its more than 15,000 staff, of whom more than 3,000 are staff researchers and the same number again are doctors and scientists who are still training. CSIC has 6% of all the staff dedicated to Research and Development in Spain, and they generate approximately 20% of all scientific production in the country.

ICTAN is placed in the premises of CSIC Campus at the Ciudad Universitaria in Madrid. ICTAN is willing to deploy R&D activities in the forefront of international knowledge and become a worldwide reference center to meet society needs in the area of food production and human well-being through nutrition. For this, it has a total staff of more than 120 people, as well as relevant facilities: Unit of Human nutrition in order to develop nutritional clinical trials; Unit of Sensory Analysis; a Pilot Plan for Food Technology; and a Unit of Analytical Services (with equipments such as mass spectrometers), among others.

Research lines of the research team

POLIFIBAN research team is focused on the study of dietary polyphenols, with especial emphasis to the so-called non-extractable polyphenols. These compounds, present if the food matrix as polymeric structures or linked to polymeric molecules such as dietary fibre (for this reason they are also called macromolecular antioxidants) are common in plant foods and they contribute to the daily intake of polyphenols. Moreover, preclinical and clinical studies have shown relevant health effects of non-extractable polyphenols rich matrixes. Nevertheless, they are still scarcely studied in the field of dietary polyphenols.

Our research team explores these compounds from a multi-disciplinary perspective, including characterization in foods, identification of new sources (including byproducts) for the production new ingredients; evaluation of in vitro bioaccessibility; evaluation of the metabolic fate of these compounds through clinical studies; evaluation of the health effects of these compounds by performing nutritional clinical trials.

We are looking for a junior scientist with experience in the field of food science and nutrition in order to join research lines through MSCA-IF 2021 funding. Potential candidates please send a CV together with a motivation letter to Dr. Jara Pérez-Jiménez (jara.perez@ictan.csic.es)

Representative publications in the last five years

Pérez-Jiménez J, Saura-Calixto F. Macromolecular antioxidants or non-extractable polyphenols in fruit and vegetables: intake in four European countries. Food Res. Intl., 74, 2015, 315-23Sanz-Pintos N, Pérez-Jiménez J, Buschmann AH, Vergara-Salinas JR, Pérez-Correa JR, Saura-Calixto F. Macromolecular antioxidants and dietary fiber in edible seaweeds. J. Food Sci., 82, 2017, 289-95.

Pérez-Ramírez I, Reynoso-Camacho R, Saura-Calixto F, Pérez-Jiménez J. Comprehensive characterization of extractable and non-extractable phenolic compounds by HPLC-ESI-QTOF of a grape/pomegranate pomace dietary supplement. J. Agric. Food Chem., 66,2018, 661-73.

Molinar-Toribio E, Fuguet E, Ramos-Romero S, Taltavull N, Méndez L, Nogués MR, Medina I, Torres JL, Pérez- Jiménez J. A high-fat high-sucrose diet affects the long-term metabolic fate of grape proanthocyanidins in rats”Eur. J. Nutr., 57,2018, 339-49.

Nascimento-Souza A, Gontijo de Paiva P, Pérez-Jiménez J, Do Carmo Castro Franceschini S, Queiroz Ribeiro A. “stimated dietary intake and major food sources of polyphenols in elderly of Viçosa, Brazil: a population-based study” Eur. J. Nutr., 57, 2018, 617-27.

Pérez-Jiménez J, Saura-Calixto F. “Fruit peels as sources of non-extractable polyphenols or macromolecular antioxidants: analysis and nutritional implications” Food Res. Intl., 111, 2018, 148-52.

Martínez-Maqueda D, Zapatera B, Gallego-Narbón A, Vaquero MP, Saura-Calixto F, Pérez-Jiménez J. A 6-weeks supplementation with grape pomace to subjects at cardiometabolic risk ameliorated insulin sensitivity, without affecting other cardiometabolic parameters. Food Function, 9, 2018, 6010-19.

Saura-Calixto F, Pérez-Jiménez J (editors). Non-extractable polyphenols and carotenoids: importance in human nutrition and health. Royal Society of Chemistry, UK, 2018, ISBN: 978-1-78801-106-8.

Amaya-Cruz D, Pérez-Ramírez I, Pérez-Jiménez J, Nava GM, Reynoso-Camacho R. “Comparison of the bioactive potential of Roselle (Hibiscus sabdariffa L.) calyx and its by-product: phenolic characterization by UPLC-QTOF MSE and their anti-obesity effect in vivo” Food Res. Intl., 2019, ID 108589

Cárdenas-Castro A, Pérez-Jiménez J, Bello-Pérez LA, Tovar J, Sáyago-Ayerdi SG. “Bioaccessibility of phenolic compounds in common beans (Phaseolus vulgaris L.) after in vitro gastrointestinal digestion: a comparison of two cooking procedures” Cereal Chem., 97, 2020, 670-80.

Ramos-Romero S, Léniz A, Martínez-Maqueda D, Busquets C, Fernández-Quintela A, Hereu M, Torres JL, Portillo MP, Pérez-Jiménez J. “Inter-individual variability in insulin response after grape pomace supplementation in subjects at high cardiometabolic risk: role of microbiota and miRNA” Molec. Nutr. Food Res., 65, 2021, 2000113.

Current research grants

Spanish Ministry of Science, Innovation and Universities (Spain), “Dietary high molecular weight flavanols as cardioprotective adjuvants in type 2 diabetes: from their molecular mechanism to their preclinical and clinical effects”, RTI2018-095059-B-I00 (Participant)

CYTED (Science and Technology for Development) International Network. “Underused native Latin American plant foods” (Participant)

National Fund for Science and Technology Development (Chile), “Development of efficient and environmentally friendly processes for the production of safe and bioactive phlorotannins extracts from Chilean seaweeds” (Participant)

Collaborations

The research team develops continuous collaboration with several national and international researchers. During the last three years active collaborations took place with the following researchers: Dr. R.M. Lamuela-Raventós and Dr. S. Ramos, University of Barcelona, Spain; Prof. J.L. Torres, Institute of Advanced Chemistry of Catolonia (IQAC-CSIC), Barcelona, Spain; Dr. M.P. Portillo, University of the Basque Country, Spain; Dr. Sonia González-Solares, University of Oviedo, Spain; Dr. L. Robaina, Las Palmas de Gran Canaria University, Spain; Dr. S. Grasso, University of Reading, United Kingdom; Dr. R. Reynoso-Camacho, Autonomous University of Querétaro, Mexico; Dr. S.G. Sáyago-Ayerdi, Tepic Technology Institute, Mexico; Dr. J.R. Pérez-Correa, Catholic University, Chile; Dr. J. Parada, Austral university, Chile.

 

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