27/03/2020

Postdoc (adjunct) in the Laboratory of Bioorganic Chemistry


  • ORGANISATION/COMPANY
    University of Warsaw
  • RESEARCH FIELD
    Chemistry
  • RESEARCHER PROFILE
    Recognised Researcher (R2)
  • APPLICATION DEADLINE
    01/06/2020 23:00 - Europe/Brussels
  • LOCATION
    Poland › Warsaw
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/08/2020

Project title: mRNA 5′ end methylation status: towards deeper understanding of biological role and identification of synthetic mimics, OPUS 17, NCN

Project description: The aim of the project is to understand how the methylation status at the 5’ end of mRNA cap structure and the few neighboring nucleotides influences biochemical properties of mRNA such as translation, turnover, and immunogenicity. These properties are of crucial importance for applicability of mRNA in gene therapies, therefore this knowledge can be used for tailoring structure of mRNA 5’ end to various therapeutic applications. The studies will cover the modifications within ribose of the first (cap 1) and the second transcribed nucleotide (cap 2) as well as methylation of the bases including 6-methyl adenosine (m6A) and 5-methylcytosine.

More information at: https://konkursydlanauczycieli.uw.edu.pl/api/document/191/datafile/pdf

 

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Job Work Location Personal Assistance locations
Work location(s)
1 position(s) available at
University of Warsaw
Poland
Warsaw
Banacha 2c

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EURAXESS offer ID: 508702

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